Common features of Prader-Willi syndrome include

• A. Hyperactivity and appetite suppression
• B. Low muscle tone and short stature
• C. Early puberty and high IQ
• D. Normal development with no obesity

Answer: (B)

Prader-Willi syndrome is typically marked by low muscle tone from birth and short stature, with obesity developing later due to an insatiable appetite. The weak muscle tone in infancy affects feeding and early motor development, while short stature is common and growth hormone deficiency is often present. Many individuals also have hypogonadism and other features like small hands/feet and learning or behavioral challenges. The option that describes low muscle tone and short stature matches these common presentations. Appetite suppression is not part of the pattern—in fact, hyperphagia tends to drive obesity. Early puberty and high IQ are not typical, given hypogonadism and often lower cognitive function, and normal development with no obesity does not fit the syndrome’s usual course.